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Progetti Europei

Progetti finanziati dalla EU o da altri enti europei

Smart and highly phosphorescent asterisks for (bio)sensors, antennae and molecular imaging

Funded by Vinci Programme
Prof. Paola Ceroni (IT partner) with Prof. Marc Gingras (University of Marseille, France)
Years: 2015-2018
The research is focused on new classes of smart luminescent compounds, whose phosphorescence is strongly enhanced in a rigid matrix, like nanoaggregates and crystals. They are potentially interesting in the fields of organic materials for optics (OLED), chemical biology (imaging), chemical sensors and nanoscience (organic nanodots). With this approach no toxic or rare element, like lanthanides, is used. The working principle of the present project is that phosphorescence can be switched on by conformational restriction due to media rigidification. Dendrtic light-harvesting antenna will be coupled to this new class of organic phosphorescent materials to enhance the brightness of the system

 

STRATUS: STRucture and dynAmics of biomolecules by Two-dimensional Ultraviolet Spectroscopy

Funded by: ERC Advanced Grant 2011
Dr. Marco Garavelli
Years: 2012-2017
Partners: Prof. Giulio Cerullo (Politecnico di Milano)
Two-dimensional (2D) nuclear magnetic resonance is a diagnostic technique that has revolutionized structural biology. A wealth of spectroscopic information can be obtained by extrapolating 2D techniques to the optical frequency domain, using ultrashort light pulses. 2D electronic spectroscopy (2DES) allows fundamentally new insights into the structure and dynamics of multi-chromophore systems, by measuring how the electronic states of chromophores interact with one another and transfer electronic excitations. This project aims at extending 2DES to the challenging and still uncharted UV-domain and applying it to study of structural and dynamic problems in biomolecules such as genomic systems and proteins. Thus, 2DES will unravel the molecular mechanisms of the photoinduced electronic intra/inter-chromophore events in DNA that are responsible for its photoprotection or photodemaging. 2DES will be also established as a new diagnostic tool for structural studies of polypeptides and proteins, providing sensitive information on the misfolding/aggregation processes responsible for a wide class of diseases. To realize the full power of 2DES, experiments will be combined with simulations and electronic calculations that are necessary to correlate the data with molecular states and structures.

 

COST Action MP1206 - Electrospun nanofibres for bio inspired composite materials and innovative industrial applications

Funded by: EC-FP7
Prof. Maria Letizia Focarete
(UNIBO participant)
Years: 2013-2017
Chair of the Action: Dr. Erich Kny (AT)
Electrospinning, an electro-hydrodynamic process is a versatile and promising platform technology for the production of electrospun nanofibrous materials consisting of diverse polymers and polymer composites. This platform process can provide bio- or oil based polymer nanofibrous materials for the fabrication of innovative biomedical devices and for the fabrication of new technical applications. By forming an interdisciplinary knowledge platform, the Action will strengthen the European R&TD on electrospun nanofibrous materials and nanofibrous composites and will generate fast progress in the state of the art. The Action will cover scientific breakthroughs and innovations in the electrospinning process itself, nanofibrous materials and nanofibrous composite advancements and the post treatment processing of electrospun materials. Applications in the biomedical and technical fields as well as health, societal and environmental issues are considered. The main outcome of the Action will be: (i) New integrated methodologies for designing and producing electrospinning nanofibres; (ii) Databases of application-relevant electrospun nanofibre properties; (iii) An up to date knowledge base on electrospun nanofibres and its applications; (iv) Tutorial material for training young researchers entering the field.